Publikationsfonds der Universität Hohenheim

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Über den Publikationsfonds der Universität Hohenheim erhalten Wissenschaftlerinnen und Wissenschaftler der Universität finanzielle Unterstützung bei der Veröffentlichung ihrer Forschungsergebnisse im Open Access. Gefördert werden Zeitschriftenartikel in Fully-Open-Access-Zeitschriften (Gold-OA) und hybriden Subskriptionszeitschriften (Hybrid-OA) sowie Monografien. Autorinnen und Autoren können online einen Förderantrag zur Finanzierungsbeteiligung ihrer Publikation stellen.

Publikationsfonds: https://kim.uni-hohenheim.de/publikationsfonds
Förderantrag: https://kim.uni-hohenheim.de/foerderantrag

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Selective coupling or genuine integration? Startups in the twin transformation
(2026) Kuckertz, Andreas; Hinderer, Sebastian
Startups actively shape innovation during the twin transformation to sustainability and digitalization. Our analysis of >21,000 ventures reveals that genuine twin-transformers, i.e., startups able to integrate digital and green technologies, are rare and primarily driven by software. While sustainable ventures readily adopt digital tools, digital ventures rarely embrace sustainability. This asymmetry reflects different configurations of complementarities between digital and sustainable technologies, which investor preferences reinforce. Eventually, this may lead to superficial coupling rather than deep integration. To address the issue, we offer targeted recommendations for practitioners, policymakers, and researchers aiming to foster scalable, hardware-based solutions critical for sustainability.
From coffee waste to wastewater treatment: optimization of hydrothermal carbonization and H₃PO₄ activation for Cr(VI) adsorption
(2026) Piccoli Miranda de Freitas, Caroline; De Freitas Batista, Gabriel; Dalmolin da Silva, Mariele; Checa Gomez, Manuel; Arauzo, Pablo J.; França da Cunha, Fernando; Kruse, Andrea
Spent coffee grounds (SCG) are an abundant agro-industrial waste, and their valorization as activated carbon (AC) offers a sustainable approach for wastewater treatment and heavy-metal remediation. However, the high energy demand of SCG activation limits large-scale application. Hydrothermal carbonization (HTC) reduces energy consumption and enhances material properties. This study evaluated the performance of activated carbon (AC) derived from SCG via HTC, followed by H₃PO₄ activation for Cr(VI) removal, and compared it with non-activated carbon obtained by HTC and pyrolysis. The results highlight the effect of chemical activation on enhancing surface area, porosity, and adsorption efficiency. The predicted optimal IN was 1624.7 mg·g⁻¹, closely matching the experimental value of 1640.1 ± 15.5 mg·g⁻¹, achieved at 426 °C, 92 min, and a hydrochar-to-H₃PO₄ ratio of 1:1.6. The optimized AC exhibited a maximum adsorption capacity (Qₑ) of 33 ± 1.1 mg·g⁻¹ and 99.4 ± 0.1 % Cr(VI) removal under pH 2, 25 mg·L⁻¹ initial concentration, and 2 g·L⁻¹ adsorbent dose. In contrast, the non-activated carbon presented a lower iodine number (1411 ± 70 mg·g⁻¹) and inferior adsorption performance, confirming the key role of H₃PO₄ activation in improving surface reactivity and adsorption sites. Chemical activation proved essential for improving Cr(VI) adsorption, with the H₃PO₄-AC exhibiting the highest capacity. These results demonstrate the potential of SCG-derived AC as a low-cost adsorbent for heavy-metal-rich industrial effluents, supporting circular economy strategies.
Genomic landscape of high‐altitude adaptation in East African mountain honey bees (Apis mellifera)
(2025) Mazzoni, Marco; Loidolt, Florian; Kersten, Sonja; Amulen, Deborah Ruth; Vudriko, Patrick; Meyer, Philipp; Scharnhorst, Victor Sebastian; Scheiner, Ricarda; Hasselmann, Martin
Understanding the evolutionary processes leading to differentiation within species is a central goal in population biology. A key process is local adaptation, for which organisms evolve traits enhancing the survival and reproduction in specific environments. Honey bees ( Apis mellifera ) in East Africa are well adapted to highland environments, showing different phenotypes, including behavior, compared to lowland bees. Despite these differences, highland and lowland honey bees show very low genetic differentiation, with the exception of two segments on chromosome 7 (r7) and chromosome 9 (r9), which were previously identified as chromosomal inversions. These inversions are rare in lowland populations, suggesting a key role in adaptation to high‐elevation habitats. In this study, we obtained 24 whole genomes from honey bees of Western Uganda and compared these with existing data from Kenya. We show that the chromosomal inversions play a pivotal role in local adaptation in both regions but with substantial differentiation. Genome‐wide analysis of polymorphism revealed additional genomic regions potentially involved in high‐altitude adaptation. The acquisition of transcriptome data from highland and lowland honey bees in Uganda has enabled the first insights into the differential expression of genes between these bees. Our findings elucidate the involvement of genes in behavioral and oxygen consumption processes. This paves the way to clarify the interplay of r7 and r9 with gene expression and to unravel the regulatory network underlying A. mellifera adaptation to high‐elevation habitats. Our study will contribute to a better understanding of the evolutionary processes in honey bee populations driven by environmental conditions.
High physical activity is associated with decreased fungiform papillae area and number, elevated sucrose recognition thresholds, and increased IL-6 levels: an observational human study
(2025) Kimmeswenger, Isabella; Gaider, Marlies; Doppelmayer, Kevin; Ley, Jakob P.; Lieder, Barbara
Background: Disease-related inflammation affects chemosensory signaling, but knowledge on the impact of exercise-induced low-grade inflammation on taste function remains scarce. Here we hypothesized that intense habitual physical activity modifies sweet taste perception via increased cytokine release. Methods: In an observational human study we compared participants (m/f) engaging in high (n = 34) and low (n = 31) levels of habitual physical activity. Salivary IL-6 and urinary 8-iso-prostaglandin F2α levels, body composition, sucrose recognition threshold, preference and consumption of sweet foods, size and area of fungiform papillae as well as selected hormones regulating food intake were recorded. Statistical analysis was conducted using Principal Component Analysis (PCA) followed by Student’s t-tests and multiple regression models. Results: The PCA summarized the main outcome variables to two principal components (PC). PC1 was primarily influenced by body composition and fungiform papillae markers, while sucrose recognition thresholds, sweet food consumption, and IL-6 levels strongly contributed to PC2. Compared to the low activity group, the high activity group showed on average an increased sucrose recognition threshold (+ 35.8 ± 12.8%), increased IL-6 concentrations (+ 25.6 ± 10.9%), higher consumptions of sweet foods (+ 18.8 ± 4.9%) and decreased number (24.8 ± 4.9%) and area (-29.8 ± 6.4%) of fungiform papillae. Conclusions: The association between modified sweet taste function markers and increased IL-6 levels suggests that inflammatory processes may contribute to exercise-related changes in chemosensory perception.
Intraspecific microbiome dynamics across the life cycle of the milkweed bug Oncopeltus fasciatus
(2026) Larner, Will; Thölke da Silva Grego, Nádia; Panfilio, Kristen A.
The microbiome is an important part of the complete nutritional and genomic profile of insects. The species-rich insect order Hemiptera (aphids, cicadas and true bugs) is highly diverse for mode of microbiome acquisition, with the conundrum that species in the seed-feeding subfamily Lygaeinae have lost obvious anatomy for housing bacteria, either in bacteriocytes or midgut crypts. Here, we characterize the microbiome of the milkweed bug Oncopeltus fasciatus as a tractable lygaeinid, using 16S rRNA gene sequencing. We assess how bacterial taxa vary between the sexes and across life history stages in a controlled environment, focusing on maternal-to-embryo transmission and distinguishing egg-stage constituents that are superficial or internal (transovarially transmitted). Among a core microbiome of 28 genera, the egg stage shows the greatest diversity, with a particular expansion of the family Comamonadaceae. We also analyse inter-individual variability in nymphs and adults and validate structured, stage-specific detection of seed material. Comparative analysis identifies Rhizobium as a notable microbiome constituent in seed-feeding Hemiptera, which we had previously shown to lack nitrogen metabolism components in the genome. Overall, we provide a nuanced assessment of bacterial abundance dynamics between individuals and across the life cycle and discuss the implications for acquisition and potential relevance as nutritional endosymbionts. This will underpin comparative investigations in seed-feeding bugs and future work in O. fasciatus on tissue-specific and diet-specific microbiome profiles, including in natural populations.
Animal welfare in non-anthropocentric cost-benefit analysis and social welfare functions: a critical review to guide practical application
(2025) Dusel, Sara; Wieck, Christine
Cost-benefit analysis and social welfare functions are two closely related methods to evaluate policy impacts. In this critical review, we present the state of knowledge on how to include the animals’ (non-anthropocentric) perspective in these policy evaluations. For this, we synthesize material from the scientific and grey literature and develop a checklist that guides through the process of non-anthropocentric cost-benefit analysis and social welfare functions. Step-by-step, the checklist gives an overview of the alternative options and normative assumptions in the literature and points to remaining research gaps.
MMP21 behaves as a fluid flow transported morphogen to impart laterality during development
(2025) Ott, Tim; Brugger, Amelie; Szenker-Ravi, Emmanuelle; Kurrle, Yvonne; Aberle, Olivia; Tisler, Matthias; Blum, Martin; Whalen, Sandra; Bouvagnet, Patrice; Reversade, Bruno; Schweickert, Axel
Heterotaxy (HTX) is frequently caused by deleterious variants in the gene encoding Matrix metallopeptidase 21 (MMP21). However, the underlying pathomechanism has not been ascertained. In this study, we report on a novel HTX-associated MMP21 knockout allele in humans and investigate the peptidase’s role during laterality development using Xenopus embryos as animal model. The targeted inactivation of mmp21 in f0 mutant Xenopus successfully phenocopied the human HTX condition, yet the cilia-driven leftward fluid flow, which initiates asymmetric gene activity at the left-right organizer (LRO), was unaltered in mmp21 null frogs. Instead, our analysis of downstream events revealed that flow response, the left-sided repression of dand5, could not take place. Remarkably, gain-of-function experiments demonstrated that Mmp21 spreads over LRO cells and triggers flow response. Additionally, Mmp21 functions upstream of Cirop, another metallopeptidase, which we found specifically localized to LRO cilia. Thus, our findings suggest that Mmp21 may be the long-sought morphogen, which is actively transported by the leftward fluid flow to Cirop-laden cilia, in order to specify the left side of the embryo.
Microbiota responses to feed particle size, calcium concentration, and phytase supplementation in broiler chickens
(2026) Rubio-Cervantes, Ismael; Wolfrum, Stephanie; Siegert, Wolfgang; Rodehutscord, Markus; Camarinha-Silva, Amélia
This research aimed to investigate the modulation of broiler-chickens gut microbiota by dietary particle size (PS), exogenous phytase, and calcium (Ca) concentration. Eight experimental diets varied in PS (fine 222 µm (PF) and coarse 309 µm (PC)), Ca concentration (4.9 and 7.2 g/kg), and exogenous phytase (0 and 1000 FTU/kg). A total of 560 Ross 308 broiler chickens were allocated to 56 metabolism units at 7 days of age and randomly assigned to each diet (7 replicates per treatment). On days 22 and 23, the birds were slaughtered, and the digesta from the gizzard, ileum, and ceca were sampled and pooled on a metabolism unit basis. DNA extraction was followed by 16S rRNA gene amplicon sequencing. Thirteen amplicon sequence variants (ASV) were present across the gizzard, ileum, and ceca, most of which were assigned to Limosilactobacillus and represented a substantial share of the total relative abundance in each section, 86 % in the gizzard, 88 % in the ileum, and 30 % in the ceca. Six of these L. reuteri ASVs were significantly enriched by coarse particle feeding, suggesting strain-specific adaptation to enhanced phosphorus availability. In the ileum, Candidatus arthromitus (p < 0.001) and Rombustia (p < 0.05) showed a significant increase in relative abundance in PC compared to PF. Phytase supplementation reduced the relative abundance of Lactobacillus and Streptococcus (p < 0.05), while higher Ca concentration decreased that of C. arthromitus (p < 0.05). In the ceca, increases in the relative abundance of Anaerostipes (p < 0.05) and Clostridia vadin BB60 were found for PC diets compared to PF (p < 0.001). The addition of phytase and Ca also significantly affected several genera, albeit the variations were less than 1 %. Dietary PS, exogenous phytase, and Ca concentration modulated the gut microbiota, specifically influencing the abundance of key microorganisms like Candidatus arthromitus, Anaerostipes, and Clostridia vadin BB60, involved in phosphorus metabolism and overall broiler chickens' health.
Coffee berry borer control, but not coffee yield, is mediated by non-additive interaction between birds and ants across different cultivation systems
(2026) Cardona Tejada, Damaris A.; Parra, Juan L.; Grass, Ingo; Schurr, Frank M.
Coffee is one of the most traded tropical crops, cultivated in some of the most biodiverse regions on the planet. Coffee production can be seriously reduced by the coffee berry borer (CBB), a specialized beetle that feeds on the endosperm of coffee berries. Given the CBB's economic relevance, coffee-producing countries have developed extensive Integrated Pest Management programs. Nonetheless, most of these programs fail to incorporate CBB control by natural enemies such as birds and ants. While the effects of birds and ants on CBB suppression have been demonstrated to be positive when studied in isolation, their interactive effects have been little studied. To better understand the effects of the trophic interaction between birds and ants on CBB control, we conducted a full-factorial block experiment excluding birds and ants from coffee shrubs. We distributed 49 experimental blocks across three different coffee systems in a Colombian landscape: sun-exposed coffee, coffee-plantain intercropping, and shade coffee. We found birds to be key control agents of CBB: in the presence of ants, bird exclusion increased CBB infestation by 36 %. However, in the absence of ants, birds had little effect on CBB infestation, demonstrating that the effects of birds and ants were non-additive. This suggests that birds control CBB through a trophic cascade mediated by ants. We also found that the effects of exclusions were modified by the cultivation system, with the shade coffee system consistently reducing CBB infestation. Our experiment demonstrates that crop diversification is an effective measure for integrating local enemies into IPM strategies. Nonetheless, we acknowledge that trophic interactions are highly complex and exhibit a context-dependency that can result in the suppression of biological pest control. Therefore, we recommend conducting future analysis on evaluating the effects of predator´s community composition to encourage the development of IPM programs that leverage biodiversity in agroecosystems.
On the structural analysis and optimal input design for joint state and parameter estimation
(2025) Lepsien, Arthur; Kügler, Philipp; Schaum, Alexander
This paper addresses the problem of joint state and parameter estimation for nonlinear affine-input systems with positive parameters including the design of a closed-loop optimal input adaptation to increase an identifiability measure for the system. The identifiability itself is considered in the context of structural observability of the system dynamics based on structural analysis of the system including the unknown parameters as additional states. In particular, the network graph-based interpretation of structural observability is employed at this point. This analysis motivates to include time derivatives of the measurements as additional system outputs to enhance the structural observability properties. For this purpose robust exact differentiation is considered, relying on the super-twisting algorithm to obtain finite time convergent estimates of these signals. Using the extended measurement signal, a continuous-discrete Extended Kalman filter is proposed that ensures strictly positive estimates for the parameters. Based on the estimates of states and parameters the input signal is determined using a moving horizon optimal predictive control that evaluates the condition number of the Fisher information matrix, thus maximizing the information content of the measurements with respect to the parameters. The proposed scheme extends and combines different previously discussed approaches from the literature and is evaluated by means of a thermal process example in simulation and experiment, showing high potential for similar system identification problems.
Motivational framing strategies in health care information security training: randomized controlled trial
(2025) Keller, Thomas; Warwas, Julia Isabella; Klein, Julia; Henkenjohann, Richard; Trenz, Manuel; Thanh-Nam Trang, Simon
Background: Information security is a critical challenge in the digital age, especially for hospitals, which are prime targets for cyberattacks due to the monetary worth of sensitive medical data. Given the distinctive security risks faced by health care professionals, tailored Security Education, Training, and Awareness (SETA) programs are needed to increase both their ability and willingness to integrate security practices into their workflows. Objective: This study investigates the effectiveness of a video-based security training, which was customized for hospital settings and enriched with motivational framing strategies to build information security skills among health care professionals. The training stands out from conventional interventions in this context, particularly by incorporating a dual-motive model to differentiate between self- and other-oriented goals as stimuli for skill acquisition. The appeal to the professional values of responsible health care work, whether absent or present, facilitates a nuanced examination of differential framing effects on training outcomes. Methods: A randomized controlled trial was conducted with 130 health care professionals from 3 German university hospitals. Participants within 2 intervention groups received either a self-oriented framing (focused on personal data protection) or an other-oriented framing (focused on patient data protection) at the beginning of a security training video. A control group watched the same video without any framing. Skill assessments using situational judgment tests before and after the training served to evaluate skill growth in all 3 groups. Results: Members of the other-oriented intervention group, who were motivated to protect patients, exhibited the highest increase in security skills (ΔM=+1.13, 95% CI 0.82-1.45), outperforming both the self-oriented intervention group (ΔM=+0.55, 95% CI 0.24-0.86; P=.04) and the control group (ΔM=+0.40, 95% CI 0.10-0.70; P=.004). Conversely, the self-oriented framing of the training content, which placed emphasis on personal privacy, did not yield significantly greater improvements in security skills over the control group (mean difference=+0.15, 95% CI –0.69 to 0.38; P>.99). Further exploratory analyses suggest that the other-oriented framing was particularly impactful among participants who often interact with patients personally, indicating that a higher frequency of direct patient contact may increase receptiveness to this framing strategy. Conclusions: This study underscores the importance of aligning SETA programs with the professional values of target groups, in addition to adapting these programs to specific contexts of professional action. In the investigated hospital setting, a motivational framing that resonates with health care professionals’ sense of responsibility for patient safety has proven to be effective in promoting skill growth. The findings offer a pragmatic pathway with a theoretical foundation for implementing beneficial motivational framing strategies in SETA programs within the health care sector.
Leveraging regionally sourced natural fibers for coreless filament winding in sustainable construction
(2026) Rossa, Alina J.; Bozó, Daniel Christopher; Mindermann, Pascal; Gresser, Götz T.; Schuenemann, Franziska
This study investigates the potential of regionally sourced natural fibers (NF) as sustainable feedstocks for coreless filament winding (CFW), an innovative and resource-efficient composite fabrication method for construction. As the sector moves towards bio-based materials, flax has emerged as a benchmark due to its compatibility with CFW and favorable mechanical properties. However, supply chain vulnerabilities and price volatility highlight the need for regional alternatives to flax fibers. By assessing hemp, miscanthus, lavender, nettle and wheat straw cultivated in Baden-Württemberg (BW), this paper links crop sustainability and fiber suitability with the broader aim of strengthening local biomass utilization within the bioeconomy. A multi-stage evaluation framework compares environmental, economic, social, and technical indicators against flax, focusing on biomass availability, input intensity, ecosystem services, land-use competition, and fiber properties. The results identify hemp as the most promising alternative due to its high fiber output, low cultivation inputs, beneficial ecosystem services and mechanical performance. Nettle offers strong mechanical performance but faces agronomic limitations, while lavender presents niche potential under integrated production systems. Miscanthus and wheat straw, while unsuitable for direct CFW due to fiber morphology, may serve as supplementary feedstocks through modified processing. These findings underscore the role of local biomass streams in creating robust regional value chains, contributing to the resilience and sustainability of the bioeconomy. While the focus of this study is on BW, the framework can be transferred to other regions and may serve as a practical tool for policy, industry, and research seeking to advance circular approaches in bio-based construction.
Sustainability certification in the digital era: a qualitative analysis of sustainability reports across product categories
(2026) Boller, Meta Leonie; Grabinger, Toni; Zurwehme, Annikka; Krupitzer, Christian
The food industry faces growing pressure to align sustainability goals with the rapid advance of digital technologies. This study explores how digitalization supports and transforms sustainability certification practices across diverse food product categories. Novelty lies in examining the interplay between digital technologies and sustainability reporting intensity, offering insights into how firms communicate and operationalize sustainability commitments. A qualitative content analysis was conducted on the sustainability reports of 21 companies using MAXQDA software, assessing the frequency and depth of reporting on sustainability focus topics and digital tools applied. The study includes multiple food product categories, such as coffee and tea, chocolate, grain products, dairy products, beverages, meat and fish, and tropical fruits. Results show that larger firms and those with higher turnover report more frequently and comprehensively on sustainability and digitalization. Three clusters of companies were identified, each reflecting shared sustainability challenges rather than specific product categories. The findings suggest that the relevance of digital technologies is more closely linked to addressing these cross-cutting sustainability challenges, and that high-value product segments provide the most promising starting points for integrating digital technologies into certification processes.
Effects of dietary phosphorus and myo-inositol supplementation on NaPi-IIb and TRPV6 protein expression in duodenal apical membranes of laying hens from two strains
(2026) Shomina, Nataliia; Sommerfeld, Vera; Hanauska, Anna; Oster, Michael; Rodehutscord, Markus; Huber, Korinna
Phosphorus (P) and calcium (Ca) absorption in the intestine is mediated by apical brush border membrane (BBM) transporters, including the sodium-dependent phosphate (Pi) transporter NaPi-IIb and the Ca²⁺-selective channel TRPV6. Both are highly expressed in the duodenum and exhibit dietary adaptability; yet little is known about how this adaptability varies with strain and age in laying hens. The present study examined the effects of dietary mineral P renunciation and myo-inositol (MI) supplementation on NaPi-IIb and TRPV6 protein expression in the duodenal BBM of Lohmann Brown-Classic (LB) and Lohmann LSL-Classic (LSL) hens. Two independent feeding trials were conducted: hens received diets either with or without mineral P supplementation (wk 15 - 19 and 20 – 24), or with graded MI levels (0 - 3 g/kg; wk 26 – 30). At the end of each period, hens were euthanized and protein expression of NaPi-IIb and TRPV6 in duodenal BBM was studied by western blotting. Statistical correlation with additional traits of mineral metabolism was analyzed. An immunoreactive NaPi-IIb band was detected at ∼ 45 kDa; therefore, all results reported here refer to this NaPi-IIb fragment. Mineral P renunciation did not affect NaPi-IIb fragment or TRPV6 expression in either hen strain. In LSL hens NaPi-IIb fragment expression increased from wk 19 to wk 24, whereas in LB hens it remained unchanged. NaPi-IIb fragment expression was positively associated with duodenal phosphatase activity and plasma estradiol. TRPV6 expression tended to reduce in LB hens from wk 19 to wk 24, but remained stable in LSL hens. TRPV6 expression was positively associated with duodeno-jejunal P content. MI supplementation upregulated NaPi-IIb fragment expression in LB, but downregulated it in LSL hens with high dietary MI levels, without affecting TRPV6. These findings demonstrate strain-dependent regulatory patterns of duodenal expression of NaPi-IIb fragment and TRPV6 in response to physiological stage and MI supply, indicating that mineral feeding strategies may benefit from genotype-specific consideration, whereas the mechanisms underlying MI-related effects require further clarification.
Workplace stressors and burnout among healthcare professionals: Insights from the pandemic and implications for future public health crises
(2025) Daneshvar, Elahe; Otterbach, Steffen
This study evaluates the prevalence of burnout among healthcare professionals (HCPs) during the COVID-19 pandemic in Iran and examines its association with key occupational stressors (workload, job control, and leadership communication). Furthermore, it proposes relevant organisational interventions for future pandemic preparedness. A cross-sectional survey of HCPs (N = 723) was conducted in four hospitals in Tehran during the third peak of the COVID-19 pandemic in Iran, including the Copenhagen Burnout Inventory and items on perceived workload, job control, and leadership communication. The study found that 67.41% of HCPs reported substantial symptoms of burnout (moderate-to-high burnout, i.e. CBI ≥ 50), with a mean score of 59.6 points. The prevalence of burnout (CBI ≥ 50) was prominent across all three dimensions—personal, work, and patient-related—at 72.86%, 69.87%, and 65.37%, respectively. The analysis demonstrated significant associations between burnout and the three foundational workplace stressors. Multivariate linear regression analysis showed that frontline, female, and married HCPs reported the highest levels of burnout. This study provides practical implications for healthcare organisations and policy makers, highlighting the need for targeted organizational interventions that could mitigate burnout during ongoing and future health crises.
Nutrient–response modeling with a single and interpretable artificial neuron
(2025) Rodehutscord, Markus; Ahmadi, Hamed
Precise estimation of nutrient requirements and utilization efficiency is fundamental to nutritional sciences, yet it is mainly performed using classical nonlinear regression models. These models are interpretable but require careful selection of the functional form and initial parameter values. Flexible machine learning (ML) methods are seemingly disliked due to their perceived “black box” nature, which can obscure biological insight. A minimal and interpretable ML framework addresses this gap in nutrient–response modeling. The proposed approach uses a single artificial neuron with a hyperbolic tangent activation. Mathematically, this resembles a four-parameter sigmoidal function but with greater flexibility and distinct parameter definitions, allowing capture of the monotonic, saturating dynamics typical of essential nutrient responses. The method is enhanced with modern ML best practices, including data augmentation, Bayesian regularization, and bootstrap resampling, providing robust, uncertainty-quantified estimates of key nutritional metrics—such as asymptotic response, inflection point, and nutrient requirements—even from small datasets. Evaluations across 12 diverse datasets from poultry and fish studies, including amino acids and phosphorus, demonstrated that the single artificial neuron matches or exceeds the performance of classical models while providing full analytical transparency. The framework is implemented as a no-code graphical application, ‘NutriCurvist’, offering an easy-to-use alternative tool for nutrient-response modeling to support data-driven, precision nutrition.
Comparing hops and malt price transmission in the beer value chain: evidence from Germany
(2025) Hess, Sebastian; Bublik, Nikolas
The German beer value chain has received limited attention so far, despite the country’s central role in global beer production. This study investigates the price dynamics of its two key inputs—hops and malt—using monthly price data from 2015 to 2024 based on a unique dataset from a German hops cooperative. While contract farming is common for both raw materials, malt is traded via private firms, whereas hops are marketed almost exclusively through farmer-owned cooperatives. A vector error correction model (VECM) is estimated, incorporating structural break dummies identified through Bai–Perron tests, followed by forecast error variance decomposition (FEVD) and impulse response function (IRF) analysis. The results show that hop prices are largely self-driven and adjust more quickly to deviations from equilibrium than malt or beer prices. While malt and beer exhibit stronger interdependencies, the hop sector displays greater price stability. The findings further reveal that the malting sector responded significantly to the recent energy price crisis in Germany, whereas the hop sector did not.
The chicken gut microbiome in conventional and alternative production systems
(2025) Cheng, Yu-Chieh; Krieger, Margret; Korves, Anna-Maria; Camarinha‑Silva, Amélia
The poultry gut microbiome plays a key role in nutrient digestion, immune function, and overall health. Differences among various farming systems, including conventional, antibiotic-free, free-range, and organic systems, influence microbial composition and function through variations in diet, genetic selection, environmental exposure, and antibiotic use. Conventional systems typically rely on formulated diets and controlled housing conditions, often with routine antimicrobial use. In contrast, organic systems emphasize natural feed ingredients, including roughage, outdoor access, and strict limitations on the use of antibiotics. These divergent practices shape the gut microbiota differently, with organic systems generally associated with greater exposure to environmental microbes and, consequently, greater microbial diversity. However, the implications of this increased diversity for poultry health and performance are complex, as organic systems may also carry a higher risk of pathogen exposure. This review summarizes current findings on the chicken gut microbiome across conventional and alternative production systems (antibiotic-free, free-range, and organic), focusing on microbial diversity, functional potential, and disease resilience. The need for standardized methodologies and consistent nomenclature in microbiome research is also discussed to improve comparability across studies. Understanding how production systems influence the gut microbiota is essential for improving poultry health and productivity while addressing challenges related to antimicrobial resistance and sustainable farming practices.
Using landscape genomics to infer genomic regions involved in environmental adaptation of soybean genebank accessions
(2025) Haupt, Max; Schmid, Karl
Background: Understanding how crops adapt to specific environmental conditions is becoming increasingly important in the face of accelerating climate change, but the genetics of local adaptation remains little understood for many crops. Landscape genomics can reveal patterns of genetic variation that indicate adaptive diversification during crop evolution and dispersal. Here, we examine genetic differentiation and association signatures with environmental gradients in soybean ( Glycine max ) germplasm groups from China that were inferred from the USDA Soybean Germplasm Collection ( N = 17, 019 accessions) based on population structure and passport information. Results: We recover genes previously known to be involved in soybean environmental adaptation and report numerous new candidate genes in adaptation signatures implicated by genomic resources such as the genome annotation and gene expression datasets to function in flowering regulation, photoperiodism and stress reaction cascades. Linkage disequilibrium network analysis suggested functional relationships between genomic regions with signatures of genetic differentiation, consistent with a polygenic nature of environmental adaptation. We tested whether haplotypes associated with environmental adaptation in China were present in 843 North American and 160 European soybean cultivars and found that haplotypes in major genes for early maturity have been selected during breeding, but also that a large number of haplotypes exhibiting putative adaptive variation for cold regions at high latitudes are underrepresented in modern cultivars. Conclusions: Our results demonstrate the value of landscape genomics analysis of genebank accessions studying crop environmental adaptation and to inform future research and breeding efforts for improved adaptation of soybean and other crops to future climates.
Can market fragmentation explain the limited success of political attempts to promote grain legume cultivation in Germany?
(2025) Mittag, Franziska; Hess, Sebastian
Grain legumes, such as field peas, field beans, sweet lupins and soybeans, are known to increase biodiversity within the appropriate crop rotation and are an important source of import-substituting feed protein. National and regional policy schemes have long tried to support the cultivation of grain legumes. Although many regions in Germany offer favourable conditions for grain legumes, previous subsidy schemes have failed to increase the area under cultivation and farmers report a lack of market incentives. Indeed, the available price data exhibit a substantial share of non-random missing values in weeks when grain legumes were not traded. We analyse these non-price periods using cointegration tests and single-hurdle Tobit models. The results indicate that regional price formation for grain legumes in German regions depends not only on a minimum quantity of the respective legume crop in supply but also on a favourable supra-regional soybean price: Regional grain legume markets are not integrated and show evidence of a fragmented market structure. This may explain why local grain legume value chains have failed to emerge in Germany, despite decades of policy attempts to support these crops.

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